Article
Ultrafast Sample placement on Existing tRees (UShER) enables real-time phylogenetics for the SARS-CoV-2 pandemic.
Nature genetics - 1 Jun 2021
Turakhia Yatish, Thornlow Bryan, Hinrichs Angie S, De Maio Nicola, Gozashti Landen, Lanfear Robert, Haussler David, Corbett-Detig Russell
Abstract excerpt
As the SARS-CoV-2 virus spreads through human populations, the unprecedented accumulation of viral genome sequences is ushering in a new era of 'genomic contact tracing'-that is, using viral genomes to trace local transmission dynamics. However, because the viral phylogeny is already so large-and will undoubtedly grow many fold-placing new sequences onto the tree has emerged as a barrier to real-time genomic...
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