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Article

Efficient comparative phylogenetics on large trees.

Bioinformatics (Oxford, England) - 15 Mar 2018

Louca Stilianos, Doebeli Michael

Abstract excerpt

Motivation: Biodiversity databases now comprise hundreds of thousands of sequences and trait records. For example, the Open Tree of Life includes over 1 491 000 metazoan and over 300 000 bacterial taxa. These data provide unique opportunities for analysis of phylogenetic trait distribution and reconstruction of ancestral biodiversity. However, existing tools for comparative phylogenetics scale poorly to such...

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PMID: 29091997
DOI: 10.1093/bioinformatics/btx701

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