Article
Identifying enhancers of innate immune signaling as broad-spectrum antivirals active against emerging viruses
20 Jun 2022
Abstract excerpt
The increasingly frequent outbreaks of pathogenic viruses have underlined the urgent need to improve our arsenal of antivirals that can be deployed for future pandemics. Innate immunity is a powerful first line of defense against pathogens, and compounds that boost the innate response have high potential to act as broad-spectrum antivirals. Here, we harnessed localization-dependent protein-complementation assays...
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