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Article

A phenotypic assay to identify Chikungunya virus inhibitors targeting the nonstructural protein nsP2.

Journal of biomolecular screening - 1 Feb 2013

Lucas-Hourani Marianne, Lupan Alexandru, Desprès Philippe, Thoret Sylviane, Pamlard Olivier, Dubois Joëlle, Guillou Catherine, Tangy Frédéric, Vidalain Pierre-Olivier, Munier-Lehmann Hélène

Abstract excerpt

Chikungunya virus (CHIKV) is a mosquito-transmitted pathogen responsible for an acute infection of abrupt onset, characterized by high fever, polyarthralgia, myalgia, headaches, chills, and rash. In 2006, CHIKV was responsible for an epidemic outbreak of unprecedented magnitude in the Indian Ocean, stressing the need for therapeutic approaches. Since then, we have acquired a better understanding of CHIKV biology,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22983165
DOI: 10.1177/1087057112460091

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