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Association of TP53 gene polymorphisms with the risk of acute lymphoblastic leukemia in Moroccan children.

Molecular biology reports - 1 Sept 2022

Skhoun Hanaa, Khattab Mohammed, Belkhayat Aziza, Takki Chebihi Zahra, Bakri Youssef, Dakka Nadia, El Baghdadi Jamila

Abstract excerpt

BACKGROUND: TP53 gene plays a pivotal role in maintaining genetic stability and prevention of malignancies. Alterations of this gene are implicated in more than half of human cancers. To the best of our knowledge, this study is the first to explore TP53 polymorphisms in Moroccan childhood acute lymphoblastic leukemia (ALL). METHODS AND RESULTS: DNA samples of 45 ALL children were obtained from peripheral blood. A...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35705773
DOI: 10.1007/s11033-022-07643-3

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