Article
HLA-C polymorphisms with susceptibility and protection against acute leukemia in a Moroccan population.
Frontiers in immunology - 1 Jan 2026
Laaziri Khalid, Brahim Ikram, Hazime Raja, Lahlimi Fatima Ezzahra, Abakarim Ouadii, Tazi Illias, El Bakkouri Jalila, Ettayebi Hanae, Ammara Mounia, Zyad Abdelmajid, Mtairag El Mostafa, Admou Brahim
Abstract excerpt
Background: Acute leukemia (AL) is a malignant hematological disorder, with two main subtypes: acute myeloid leukemia (AML) and acute lymphoblastic leukemia (ALL). The incidence rate of AML and ALL is estimated at approximately 2.7 and 1.5 per 100,000 people, respectively, with an overall mortality rate of approximately 23.6%. This study aimed to investigate the association between human leukocyte antigen (HLA)-C...
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