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Article

The MTHFR C677T polymorphism and risk of acute lymphoblastic leukemia: an updated meta-analysis based on 37 case-control studies.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2013

Jiang Yuan, Hou Jing, Zhang Qiang, Jia Shu-Ting, Wang Bo-Yuan, Zhang Ji-Hong, Tang Wen-Ru, Luo Ying

Abstract excerpt

BACKGROUND: The C677T polymorphism of the methylenetetrahydrofolate reductase (MTHFR) has been associated with acute lymphoblastic leukemia (ALL). However, results were conflicting. The aim of this study was to quantitatively summarize the evidence for the MTHFRC677T polymorphism and ALL risk. METHODS: Electronic searches of PubMed and the Chinese Biomedicine database were conducted to select case-control studies...

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Source

Identifiers

PMID: 24377532
DOI: 10.7314/apjcp.2013.14.11.6357

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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