Article
Clinical and biological relevance of CREB3L1 in Philadelphia chromosome-negative myeloproliferative neoplasms.
Leukemia research - 1 Aug 2022
De Marchi Federico, Okuda Maho, Morishita Soji, Imai Misa, Baba Terumi, Horino Mei, Mori Yosuke, Furuya Chiho, Ogata Satoko, Yang Yinjie, Ando Jun, Ando Miki, Araki Marito, Komatsu Norio
Abstract excerpt
Cyclic AMP-response element-binding protein 3-like 1 (CREB3L1) is a gene involved in the unfolded protein response (UPR). Recently, we demonstrated that CREB3L1 is specifically overexpressed in the platelets of patients with Philadelphia chromosome-negative myeloproliferative neoplasms (MPNs). In this study, we aimed to show the clinical and biological relevance of CREB3L1 in these hematological diseases....
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