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Article

Role of cyclic AMP response element binding protein in human leukemias.

Cancer - 1 Nov 2005

Shankar Deepa B, Cheng Jerry C, Sakamoto Kathleen M

Abstract excerpt

Acute myeloid leukemia (AML) in adults has a 20% 5-year disease-free survival despite treatment with aggressive cytotoxic chemotherapy. Previous work from our laboratory demonstrated that the majority of patients with acute lymphoid and myeloid leukemia overexpress CREB in the bone marrow. CREB overexpression is associated with poor initial outcome of clinical disease in AML patients. CREB is a transcription...

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Identifiers

PMID: 16196046
DOI: 10.1002/cncr.21401

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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