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CREB and Leukemogenesis

1 Jan 2011

Abstract excerpt

Acute myeloid leukemia (AML) is one of the most common leukemias with a 20% 5-year event-free survival in adults and 50% overall survival in children, despite aggressive chemotherapy treatment and bone marrow transplantation. The incidence and mortality rates for acute leukemia have only slightly decreased over the last 20 years, and therefore greater understanding of the molecular mechanisms associated with...

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PMID: 22150306
DOI: 10.1615/critrevoncog.v16.i1-2.50

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