Article
Involvement of CREB3L1 in erythropoiesis induced by JAK2 exon 12 mutation.
Experimental hematology - 1 Nov 2024
Okuda Maho, Araki Marito, De Marchi Federico, Morishita Soji, Imai Misa, Fukada Hanaka, Ando Miki, Komatsu Norio
Abstract excerpt
CREB3L1, a gene encoding the endoplasmic reticulum stress transducer, is specifically overexpressed in platelet RNA from patients with myeloproliferative neoplasms (MPNs). However, the pathophysiological roles of CREB3L1 overexpression remain unclear. In the present study, we aimed to study CREB3L1 messenger RNA (mRNA) expression in the red blood cells (RBCs) of patients with MPN and its role in erythrocytosis....
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