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Article

Lamin A and telomere maintenance in aging: Two to Tango.

Mutation research - 1 Jan 2000

Sengupta Duhita, Sengupta Kaushik

Abstract excerpt

Lamin proteins which constitute the nuclear lamina in almost all higher eukaryotes, are mainly of two types A & B encoded by LMNA and LMNB1/B2 genes respectively. While lamin A remains the principal product of LMNA gene, variants like lamin C, C2 and A∆10 are also formed as alternate splice products. Role of lamin A in aging has been highlighted in recent times due to its association with progeroid or premature...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35687934
DOI: 10.1016/j.mrfmmm.2022.111788

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