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Article

Predicting CRISPR/Cas9 Repair Outcomes by Attention-Based Deep Learning Framework.

Cells - 5 Jun 2022

Liu Xiuqin, Wang Shuya, Ai Dongmei

Abstract excerpt

As a simple and programmable nuclease-based genome editing tool, the CRISPR/Cas9 system has been widely used in target-gene repair and gene-expression regulation. The DNA mutation generated by CRISPR/Cas9-mediated double-strand breaks determines its biological and phenotypic effects. Experiments have demonstrated that CRISPR/Cas9-generated cellular-repair outcomes depend on local sequence features. Therefore, the...

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Identifiers

PMID: 35681543
DOI: 10.3390/cells11111847
PMCID: PMC9180579

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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