Article
Admixture Mapping in African Americans Identifies New Risk Loci for HCV-Related Cirrhosis.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association - 1 Apr 2023
Kim Hyun-Seok, Shetty Priya B, Tsavachidis Spiridon, Dong Jing, Amos Christopher I, El-Serag Hashem B, Thrift Aaron P
Abstract excerpt
BACKGROUND & AIMS: Cirrhosis is the main predisposing condition for hepatocellular carcinoma. Host genetic risk factors have been reported for cirrhosis; however, whether there is a genetic contribution to racial disparities in cirrhosis requires further investigation. METHODS: We used an affected-only mapping by admixture linkage disequilibrium analysis to characterize the genetic risk of cirrhosis in 227...
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