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Systematic Chromatin Accessibility Analysis Based on Different Immunological Subtypes of Clear Cell Renal Cell Carcinoma

16 Apr 2021

Abstract excerpt

Background Recent research of clear cell renal cell carcinoma (ccRCC) is focused on the tumor immune microenvironment (TIME). Chromatin accessibility is critical for regulation of gene expression. However, its role in different immunological subtypes of ccRCC based on immune cell infiltration has not been systematically studied. Methods Five hundred thirty patient data from The Cancer Genome Atlas Kidney Renal...

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PMID: 33937014
DOI: 10.3389/fonc.2021.575425

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