Article
Association of Interleukin-1 Beta and Interleukin-1 Receptor Antagonist Gene Polymorphisms and Plasma Levels with Diabetic Nephropathy.
BioMed research international - 1 Jan 2022
Liao Xueling, Xiao Yanan, Elbelt Ulf, Weylandt Karsten H, Li Kanghui, Deng Jie, Zeng Ning, Xue Chao
Abstract excerpt
Objective: We investigated the relationships between interleukin- (IL-) 1β and IL-1 receptor antagonist (IL-1Ra) gene polymorphism and plasma levels in patients with diabetic nephropathy (DN). Methods: The genotype and allele frequency distribution of IL-1β and IL-1Ra in 61 patients with DN and 48 healthy controls (HCs) were determined by kompetitive allele-specific PCR (KASP), and the plasma concentrations of...
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