Article
Genetic association between interleukin-10 gene rs1518111 and rs3021094 polymorphisms and risk of type 1 diabetes and diabetic nephropathy in Egyptian children and adolescents.
Pediatric diabetes - 1 Jun 2021
El Helaly Rania Mostafa, Elzehery Rasha Rizk, El-Emam Ola Ali, El Domiaty Huda Ahmed, Elbohy Wesam Reda, Aboelenin Hadil Mohamed, Salem Nanees Abdel-Badie
Abstract excerpt
OBJECTIVE: Genetic and environmental factors have been implicated in etiopathogenesis and progression of type 1 diabetes mellitus (T1DM) and diabetic nephropathy (DN). Genetic association between interleukin-10 (IL-10) single nucleotide polymorphisms (SNPs) with T2DM and DN was recently established. We aimed to explore the potential genetic risk of IL-10 gene rs1518111 and rs3021094 SNPs in susceptibility to T1DM...
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