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Detection of infiltrating fibroblasts by single-cell transcriptomics in human kidney allografts

3 Jun 2022

Abstract excerpt

We tested the hypothesis that single-cell RNA-sequencing (scRNA-seq) analysis of human kidney allograft biopsies will reveal distinct cell types and states and yield insights to decipher the complex heterogeneity of alloimmune injury. We selected 3 biopsies of kidney cortex from 3 individuals for scRNA-seq and processed them fresh using an identical protocol on the 10x Chromium platform; (i) HK: native kidney...

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Share to Renal and Vascular Pathologies
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PMID: 35657798
DOI: 10.1371/journal.pone.0267704

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