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Single-cell transcriptomic profiling of kidney fibrosis identifies a novel specific fibroblast marker and putative disease target

2022-09-13

Abstract excerpt

<h4>Background</h4> Persistent kidney fibroblast activation and tubular epithelial cell (TEC) injury are key contributors to CKD. However, transcriptional and cellular identities of advanced kidney disease, along with renal fibroblast specific markers and molecular targets contributing to persistent tubular injury, remain elusive. <h4>Methods</h4> We performed single-cell RNA sequencing with two clinically relev...

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Literature Corpus work
a7e66730-212b-57a3-a666-a4784cd4ac93
DOI
10.1101/2022.09.13.507855
Open publication

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Single-cell transcriptomic profiling of kidney fibrosis identifies a novel specific fibroblast marker and putative disease targetDOI 10.1101/2022.09.13.507855
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