Article
Rh Blood Group D Antigen Genotyping Using a Portable Nanopore-based Sequencing Device: Proof of Principle.
Clinical chemistry - 1 Sept 2022
Tounsi Wajnat A, Lenis Vasileios P, Tammi Silja M, Sainio Susanna, Haimila Katri, Avent Neil D, Madgett Tracey E
Abstract excerpt
BACKGROUND: Nanopore sequencing is direct sequencing of a single-stranded DNA molecule using biological pores. A portable nanopore-based sequencing device from Oxford Nanopore Technologies (MinION) depends on driving a DNA molecule through nanopores embedded in a membrane using a voltage. Changes in current are then measured by a sensor, thousands of times per second and translated to nucleobases. METHODS:...
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