Article

A Multiplex Pharmacogenetics Assay using the MinION Nanopore Sequencing Device

2019-02-28

Abstract excerpt

<h4>Aim</h4> The MinION nanopore sequencing device opens the opportunity to cost-effective and point-of-care DNA sequencing. We developed a multiplex assay targeting pharmacogenetic variants related to clopidogrel and warfarin, two commonly used drugs that show response variability due to genetic polymorphisms. <h4>Materials & Methods</h4> Six reference and 78 clinical DNA samples were amplified by PCR to genera...

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Literature Corpus work: 243bb705-cab8-5240-a142-e47926d65ba3
DOI: 10.1101/563262

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