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Mosaic loss of chromosome Y in peripheral blood cells is associated with age-related macular degeneration in men

31 May 2022

Abstract excerpt

BACKGROUND: Age-related macular degeneration (AMD) is the leading cause of severe vision loss in patients over 55 years old in the industrialized world. In the past 20 years, approximately 288 million patents have been affected by this disease. Despite this high prevalence, the molecular mechanism for AMD remains unclear, and there remains no effective treatment for this disease. The mosaic loss of Y chromosome...

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PMID: 35642040
DOI: 10.1186/s13578-022-00811-9

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