Back to search

Article

Integrated bioinformatics analysis of aberrantly-methylated differentially-expressed genes and pathways in age-related macular degeneration

2020-03-19

Abstract excerpt

<h4>Background: </h4> Age-related macular degeneration (AMD) represents the leading cause of visual impairment in the aging population. The goal of this study was to identify aberrantly-methylated, differentially-expressed genes (MDEGs) in AMD and explore the involved pathways via integrated bioinformatics analysis. <h4>Methods:</h4> Data from expression profile GSE29801 and methylation profile GSE102952 were obta...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
3254f8df-d653-52d7-9f80-314f8346f536
DOI
10.21203/rs.2.20696/v3
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Integrated bioinformatics analysis of aberrantly-methylated differentially-expressed genes and pathways in age-related macular degenerationDOI 10.21203/rs.2.20696/v3
Integrated bioinformatics analysis of aberrantly-methylated differentially-expressed genes and pathways in age-related macular degenerationSemantic proximity
Identification of differentially expressed and methylated genes and construction of a co-expression network in age-related macular degenerationSemantic proximity
Integrated Microarray and RNAseq Transcriptomic Analysis of Retinal Pigment Epithelium/Choroid in Age-Related Macular DegenerationSemantic proximity
Screening of Crucial Differentially-Methylated/Expressed Genes for Alzheimer’s DiseaseSemantic proximity
Patterns of Gene Expression, Splicing, and Allele-Specific Expression Vary among Macular Tissues and Clinical Stages of Age-Related Macular Degeneration.Semantic proximity
Differential Gene Expression in Age-Related Macular Degeneration.Semantic proximity
A systems biology approach uncovers novel disease mechanisms in age-related macular degenerationSemantic proximity
Potential mechanisms of epigenetic regulation in diabetic retinopathy from the perspectives of multi-omicsSemantic proximity
Identification of key biomarkers in Diabetic retinopathy and age-related macular degeneration by integrated bioinformatics analysisSemantic proximity
An Updated Review of the Epigenetic Mechanism Underlying the Pathogenesis of Age-related Macular DegenerationSemantic proximity
AMD-associated genes encoding stress-activated MAPK pathway constituents are identified by interval-based enrichment analysis.Semantic proximity
High-throughput sequencing and Co-expression network analysis of LncRNAs and mRNAs of PBMCs in AMD patientsSemantic proximity
Select a neighboring publication to make it the new centre.