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Integrated bioinformatics analysis of aberrantly-methylated differentially-expressed genes and pathways in age-related macular degeneration

24 Mar 2020

Abstract excerpt

BACKGROUND: Age-related macular degeneration (AMD) represents the leading cause of visual impairment in the aging population. The goal of this study was to identify aberrantly-methylated, differentially-expressed genes (MDEGs) in AMD and explore the involved pathways via integrated bioinformatics analysis. METHODS: Data from expression profile GSE29801 and methylation profile GSE102952 were obtained from the Gene...

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PMID: 32209064
DOI: 10.1186/s12886-020-01392-2

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