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The Long-Term Culture of Human Fibroblasts Reveals a Spectroscopic Signature of Senescence

23 May 2022

Abstract excerpt

Aging is a complex process which leads to progressive loss of fitness/capability/ability, increasing susceptibility to disease and, ultimately, death. Regardless of the organism, there are some features common to aging, namely, the loss of proteostasis and cell senescence. Mammalian cell lines have been used as models to study the aging process, in particular, cell senescence. Thus, the aim of this study was to...

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Share to Genetics, Aging, and Longevity in Model Organisms
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PMID: 35628639
DOI: 10.3390/ijms23105830

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