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Article

Effect of Antioxidants on the Fibroblast Replicative Lifespan In Vitro

23 Sept 2020

Abstract excerpt

Replicative senescence is an unalterable growth arrest of primary cells in the culture system. It has been reported that aging in vivo is related to the limited replicative capacity that normal somatic cells show in vitro . If oxidative damage contributes to the lifespan limitation, antioxidants are expected to extend the replicative lifespan of fibroblasts. This article critically reviews the results of...

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PMID: 33029282
DOI: 10.1155/2020/6423783

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