Article
The highly unnatural fatty acid profile of cells in culture.
Progress in lipid research - 1 Jan 2020
Else Paul L
Abstract excerpt
The fatty acid profile of cells in culture are unlike those of natural cells with twice the monounsaturated (MUFA) and half the polyunsaturated fatty acids (PUFA) level (Mol%). This is not due to cell lines primarily being derived from cancers but is due to limited access to lipid and an inability to make PUFA de novo as vertebrate cells. Classic culture methods use media with 10% serum (the only exogenous source...
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