Article
Endometrioid Versus Seromucinous Borderline Ovarian Tumors: Divergent Molecular Signatures and a Shared Role as Precursors to Endometrioid Carcinoma.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists - 1 Jul 2026
Niu Shuang, Molberg Kyle, Carrick Kelley, Colon Glorimar Rivera, Gwin Katja, Zheng Wenxin, SoRelle Jeffrey A, Castrillon Diego H, Lucas Elena, Chen Hao
Abstract excerpt
Endometrioid borderline tumors (EBTs) and seromucinous borderline tumors (SMBTs) are rare ovarian neoplasms with distinct histologic features. However, the molecular profiles of EBTs and SMBTs remain incompletely characterized. We performed histologic evaluation and DNA/RNA next-generation sequencing (NGS) using a 1425-gene pan-cancer panel on 11 EBTs and 10 SMBTs to define their mutational landscapes, conduct...
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