Article
The molecular pathology of ovarian serous borderline tumors.
Annals of oncology : official journal of the European Society for Medical Oncology - 1 Apr 2016
Malpica A, Wong K-K
Abstract excerpt
Molecular studies in ovarian serous borderline tumors (OSBTs) have been used to understand different aspects of this neoplasm. (i) Pathogenesis, Kras and Braf mutations represent very early events in the tumorigenesis of OSBT as both are detected in serous cystadenomas associated with OSBTs. In contrast, serous cystadenomas without OSBTs do not show Kras or Braf mutations. In OSBTs, Kras mutations range from 17%...
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