Article
Molecular genetic analysis of ovarian serous cystadenomas.
Laboratory investigation; a journal of technical methods and pathology - 1 Jun 2004
Cheng Eric J, Kurman Robert J, Wang Menglin, Oldt Robert, Wang Brant G, Berman David M, Shih Ie-Ming
Abstract excerpt
Ovarian serous cystadenomas are common ovarian lesions that may be precursors of serous borderline tumors, which can in turn progress to low-grade serous carcinomas. It has been shown that low-grade serous carcinoma and serous borderline tumors are characterized by frequent mutations in BRAF or KRAS genes, but the mutational status of these genes in serous cystadenomas and the clonal nature of serous cystadenomas...
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