Article
PIK3CA Mutation as Potential Poor Prognostic Marker in Asian Female Breast Cancer Patients Who Received Adjuvant Chemotherapy.
Current oncology (Toronto, Ont.) - 19 Apr 2022
Cho Yoon Ah, Ko Seung Yeon, Suh Yong Joon, Kim Sanghwa, Park Jung Ho, Park Hye-Rim, Seo Jinwon, Choi Hyo Geun, Kang Ho Suk, Lim Hyun, Park Ha Young, Kwon Mi Jung
Abstract excerpt
Background: The prognostic relevance of the PIK3CA mutation together with PD-L1, c-Met, and mismatch repair deficiency (dMMR) have not been fully investigated in Asian women with breast cancer (BC) who have undergone postoperative adjuvant chemotherapy. Methods: We analyzed PIK3CA mutations via peptide nucleic acid (PNA)-mediated real-time PCR assay, PD-L1/c-Met expression via immunohistochemistry (IHC), and...
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