Article
Genomic alterations and radioresistance in breast cancer: an analysis of the ProfiLER protocol.
Annals of oncology : official journal of the European Society for Medical Oncology - 1 Nov 2017
Bernichon E, Vallard A, Wang Q, Attignon V, Pissaloux D, Bachelot T, Heudel P E, Ray-Coquard I, Bonnet E, de la Fouchardière A, Faure C, Chopin N, Beurrier F, Racadot S, Sunyach M P, Rancoule C, Perol D, Corset V, Agrapart V, Tinquaut F, Blay J-Y, Magné N, Trédan O
Abstract excerpt
BACKGROUND: Breast cancer (BC) patients with comparable prognostic features have heterogeneous outcomes, party related to a possible radiotherapy resistance leading to local-regional recurrences (LRR). The objective of the present study was to identify predictive molecular biomarkers of LRR of BC. PATIENTS AND METHODS: Genetic profile of 146 BC patients' tumours included in the ProfiLER clinical trial...
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