Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The DNA/RNA helicase DHX9 contributes to the transcriptional program of the androgen receptor in prostate cancer

19 May 2022

Abstract excerpt

BACKGROUND: Prostate cancer (PC) is the most commonly diagnosed male malignancy and an important cause of mortality. Androgen deprivation therapy is the first line treatment but, unfortunately, a large part of patients evolves to a castration-resistant stage, for which no effective cure is currently available. The DNA/RNA helicase DHX9 is emerging as an important regulator of cellular processes that are often...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Estrogen and related hormone effects
Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
Share to Prostate Cancer Treatment and Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35590370
DOI: 10.1186/s13046-022-02384-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The DNA/RNA helicase DHX9 contributes to the transcriptional program of the androgen receptor in prostate cancerPMID 35590370Read ↗

Regulation of Androgen-Responsive Transcription by the Chromatin Remodeling Factor CHD8Semantic proximity Read ↗

CHD6 promotes broad nucleosome eviction for transcriptional activation in prostate cancer cellsSemantic proximity Read ↗

Genomic analysis of DNA repair genes and androgen signaling in prostate cancerSemantic proximity Read ↗

Frequent Disruption of Chromodomain Helicase DNA-Binding Protein 8 (CHD8) and Functionally Associated Chromatin Regulators in Prostate CancerSemantic proximity Read ↗

BRD9 Expression, Alteration, Survival And Pathway Analysis In 11 Independent Prostate Cancer CohortsSemantic proximity Read ↗

MicroRNA-like snoRNA-derived RNAs (sdRNAs) promote castration resistant prostate cancerSemantic proximity Read ↗

Increased AR expression in castration-resistant prostate cancer rapidly induces AR signaling reprogramming with the collaboration of EZH2Semantic proximity Read ↗

The long noncoding RNA H19 regulates tumor plasticity in neuroendocrine prostate cancerSemantic proximity Read ↗

CRISPR screening identifies regulators of enhancer-mediated androgen receptor transcription in advanced prostate cancerSemantic proximity Read ↗

A genome-scale CRISPR screen reveals PRMT1 as a critical regulator of androgen receptor signaling in prostate cancerSemantic proximity Read ↗

Epigenomic Regulation of Androgen Receptor Signaling: Potential Role in Prostate Cancer TherapySemantic proximity Read ↗

Systematic characterization of chromatin modifying enzymes identifies KDM3B as a critical regulator in castration resistant prostate cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.