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Article

Regulation of Androgen-Responsive Transcription by the Chromatin Remodeling Factor CHD8

23 Mar 2010

Abstract excerpt

The androgen receptor (AR) mediates the effect of androgens through its transcriptional function during both normal prostate development and in the emergence and progression of prostate cancer. AR is known to assemble coactivator complexes at target promoters to facilitate transcriptional activation in response to androgens. Here we identify the ATP-dependent chromatin remodeling factor chromodomain helicase...

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Share to Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
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Identifiers

PMID: 20308527
DOI: 10.1210/me.2009-0421

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