Article

MicroRNA-like snoRNA-derived RNAs (sdRNAs) promote castration resistant prostate cancer

2021-12-20

Abstract excerpt

<h4>ABSTRACT</h4> We have identified 38 specifically excised, differentially expressed snoRNA fragments (sdRNAs) in TCGA prostate cancer (PCa) patient samples as compared to normal prostate controls. SnoRNA-derived fragments sdRNA-D19b and -A24 emerged among the most differentially expressed and were selected for further experimentation. We found that overexpression of either sdRNA significantly increased PC3 (a...

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Literature Corpus work: f807ff43-4eb9-5275-b7e3-7557af99a351
DOI: 10.1101/2021.12.17.473174

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