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Article

Genomic analysis of DNA repair genes and androgen signaling in prostate cancer

10 Oct 2018

Abstract excerpt

BACKGROUND: The cellular effects of androgen are transduced through the androgen receptor, which controls the expression of genes that regulate biosynthetic processes, cell growth, and metabolism. Androgen signaling also impacts DNA damage signaling through mechanisms involving gene expression and transcription-associated DNA damaging events. Defining the contributions of androgen signaling to DNA repair is...

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Share to Epigenetics and DNA Methylation
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PMID: 30305041
DOI: 10.1186/s12885-018-4848-x

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