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Article

Renal Cyp3a5-Expressing Genotype Decreases Tacrolimus-to-Dose Ratio in Small Cohort of Renal Transplant Recipients-Preliminary Report.

Transplantation proceedings - 1 May 2022

Warzyszyńska Karola, Zawistowski Michał, Karpeta Edyta, Jałbrzykowska Agnieszka, Kosieradzki Maciej

Abstract excerpt

BACKGROUND: Previous reports have established that patient CYP3A5 allelic variability may be the most important genetic contributor to interindividual variation in tacrolimus exposure in renal transplant recipients. However, CYP3A5 protein is expressed in the allogenic kidney. The aim of this study was to investigate the role of the renal CYP3A5 genotype in tacrolimus concentration-to-dose ratio within 3 years...

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Source

Identifiers

PMID: 35570009
DOI: 10.1016/j.transproceed.2022.02.018

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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