Article
Effect of CYP3A5 genotype on renal allograft recipients treated with tacrolimus.
Transplantation proceedings - 1 Jun 2009
Chen J S, Li L S, Cheng D R, Ji S M, Sun Q Q, Cheng Z, Wen J Q, Sha G Z, Liu Z H
Abstract excerpt
OBJECTIVE: Tacrolimus concentrations are associated with CYP3A5 genotype. The purpose of this study was to evaluate the outcomes and drug concentrations/doses among a posttransplant population with various CYP3A5 genotypes within 12 months. METHODS: Sixty seven kidney recipients receiving immunosuppression with tacrolimus + mycophenolate mofetil + prednisolone were grouped according to their CYP3A5 genotypes...
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