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Article

Driver gene detection through Bayesian network integration of mutation and expression profiles.

Bioinformatics (Oxford, England) - 13 May 2022

Chen Zhong, Lu You, Cao Bo, Zhang Wensheng, Edwards Andrea, Zhang Kun

Abstract excerpt

MOTIVATION: The identification of mutated driver genes and the corresponding pathways is one of the primary goals in understanding tumorigenesis at the patient level. Integration of multi-dimensional genomic data from existing repositories, e.g., The Cancer Genome Atlas (TCGA), offers an effective way to tackle this issue. In this study, we aimed to leverage the complementary genomic information of individuals...

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Identifiers

PMID: 35561191
DOI: 10.1093/bioinformatics/btac203
PMCID: PMC9113331

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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