Article
Cancer driver gene discovery through an integrative genomics approach in a non-parametric Bayesian framework.
Bioinformatics (Oxford, England) - 15 Feb 2017
Yang Hai, Wei Qiang, Zhong Xue, Yang Hushan, Li Bingshan
Abstract excerpt
Motivation: Comprehensive catalogue of genes that drive tumor initiation and progression in cancer is key to advancing diagnostics, therapeutics and treatment. Given the complexity of cancer, the catalogue is far from complete yet. Increasing evidence shows that driver genes exhibit consistent aberration patterns across multiple-omics in tumors. In this study, we aim to leverage complementary information encoded...
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