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Article

Identification of driver modules in pan-cancer via coordinating coverage and exclusivity.

Oncotarget - 30 May 2017

Gao Bo, Li Guojun, Liu Juntao, Li Yang, Huang Xiuzhen

Abstract excerpt

It is widely accepted that cancer is driven by accumulated somatic mutations during the lifetime of an individual. Cancer mutations may target relatively small number of cell functional modules. The heterogeneity in different cancer patients makes it difficult to identify driver mutations or functional modules related to cancer. It is biologically desired to be capable of identifying cancer pathway modules...

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Identifiers

PMID: 28415609
DOI: 10.18632/oncotarget.16433
PMCID: PMC5482642

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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