Article

Individualized discovery of rare cancer drivers in global network context

2021-10-05

Abstract excerpt

Late advances in genome sequencing expanded the space of known cancer driver genes several-fold. However, most of this surge was based on computational analysis of somatic mutation frequencies and/or their impact on the protein function. On the contrary, experimental research necessarily accounted for functional context of mutations interacting with other genes and conferring cancer phenotypes. Eventually, just su...

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Literature Corpus work: 346f184a-1a32-512d-9564-c6881486792d
DOI: 10.1101/2021.10.04.463007

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