Article
Update on NAFLD genetics: From new variants to the clinic.
Journal of hepatology - 1 Jun 2020
Trépo Eric, Valenti Luca
Abstract excerpt
Non-alcoholic fatty liver disease (NAFLD) is the leading cause of liver diseases in high-income countries and the burden of NAFLD is increasing at an alarming rate. The risk of developing NAFLD and related complications is highly variable among individuals and is determined by environmental and genetic factors. Genome-wide association studies have uncovered robust and reproducible associations between variations...
Topics
- Alleles
- Animals
- Body Mass Index
- Drug Discovery
- Epistasis, Genetic
- Gene Frequency
- Gene-Environment Interaction
- Genetic Loci
- Genetic Predisposition to Disease
- Genome-Wide Association Study
- Humans
