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Article

Effects of PNPLA3, TM6SF2 and SAMM50 on the development and severity of non-alcoholic fatty liver disease in children.

Pediatric obesity - 1 Feb 2022

Lee Kyung Jae, Moon Jin Soo, Kim Nan Young, Ko Jae Sung

Abstract excerpt

BACKGROUND: Although genetic variants of PNPLA3, TM6SF2 and SAMM50 have been reported to increase the risk of non-alcoholic fatty liver disease (NAFLD), no pediatric studies have evaluated the association between SAMM50 and NAFLD. OBJECTIVE: This study aimed to investigate the risk factors, including genetic variants, of pediatric NAFLD. METHODS: NAFLD was defined as the presence of hepatic steatosis on...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34490745
DOI: 10.1111/ijpo.12852

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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