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Article

Association between variants in the interferon lambda 4 locus and substitutions in the hepatitis C virus non-structural protein 5A.

Journal of hepatology - 1 Sept 2015

Akamatsu Sakura, Hayes C Nelson, Ochi Hidenori, Uchida Takuro, Kan Hiromi, Murakami Eisuke, Abe Hiromi, Tsuge Masataka, Miki Daiki, Akiyama Rie, Hiraga Nobuhiko, Imamura Michio, Aikata Hiroshi, Kawaoka Tomokazu, Kawakami Yoshiiku, Chayama Kazuaki

Abstract excerpt

BACKGROUND & AIMS: Single nucleotide polymorphisms within the interferon lambda 4 (IFNL4) locus are strongly associated with spontaneous clearance of hepatitis C virus (HCV) infection and early viral response to interferon therapy. Interaction between host genotype and amino acid substitutions mi...

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Source

Identifiers

PMID: 25849245
DOI: 10.1016/j.jhep.2015.03.033

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25849245-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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