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Article

A loss-of-function polymorphism in ATG16L1 compromises therapeutic outcome in head and neck carcinoma patients.

Oncoimmunology - 1 Jan 2022

Le Naour Julie, Sztupinszki Zsofia, Carbonnier Vincent, Casiraghi Odile, Marty Virginie, Galluzzi Lorenzo, Szallasi Zoltan, Kroemer Guido, Vacchelli Erika

Abstract excerpt

The anticancer immune response is shaped by immunogenic cell stress and death pathways. Thus, cancer cells can release danger-associated molecular patterns that act on pattern recognition receptors expressed by dendritic cells and their precursors to elicit an antitumor immune response. Here, we investigated the impact of single nucleotide polymorphisms (SNPs) in genes affecting this cancer-immunity dialogue in...

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Source

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Identifiers

PMID: 35481288
DOI: 10.1080/2162402X.2022.2059878
PMCID: PMC9037530

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A loss-of-function polymorphism in ATG16L1 compromises therapeutic outcome in head and neck carcinoma patients.PMID 35481288Read ↗

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