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Article

Analysis of autophagy gene polymorphisms in Spanish patients with head and neck squamous cell carcinoma.

Scientific reports - 31 Jul 2017

Fernández-Mateos Javier, Seijas-Tamayo Raquel, Klain Juan Carlos Adansa, Borgoñón Miguel Pastor, Pérez-Ruiz Elisabeth, Mesía Ricard, Del Barco Elvira, Coloma Carmen Salvador, Dominguez Antonio Rueda, Daroqui Javier Caballero, Fernández Ruiz Encarnación, Cruz-Hernández Juan Jesús, González-Sarmiento Rogelio

Abstract excerpt

Head and neck squamous cell carcinoma (HNSCC) is the sixth cancer on incidence worldwide. Tobacco and alcohol consumption are the most classical risk factors associated with its development. Autophagy process has a dual effect both in tumourigenesis and tumour suppressing activity. To investigate the importance of this pathway in HNSCC susceptibility, a risk factor matched case-control association study was...

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Identifiers

PMID: 28761177
DOI: 10.1038/s41598-017-07270-0
PMCID: PMC5537226

Genes

ATG10
ATG5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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