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Article

Nickel penetration into stratum corneum in FLG null carriers-A human experimental study.

Contact dermatitis - 1 Aug 2022

Julander Anneli, Liljedahl Emelie Rietz, Korres de Paula Helena, Assarsson Eva, Engfeldt Malin, Littorin Margareta, Shobana Anto Christine, Lidén Carola, Broberg Karin

Abstract excerpt

BACKGROUND: The filaggrin gene (FLG) plays a role in skin diseases, with the skin barrier function being impaired in FLG null carriers. The role of FLG status in relation to nickel penetration into the skin remains unclear. OBJECTIVES: To elucidate the association between FLG status and nickel penetration into stratum corneum (SC) in individuals without self-reported history of nickel allergy. METHODS: Forty...

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Identifiers

PMID: 35474514
DOI: 10.1111/cod.14137
PMCID: PMC9544599

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