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Article

Filaggrin mutations are strongly associated with contact sensitization in individuals with dermatitis.

Contact dermatitis - 1 May 2013

Thyssen Jacob P, Linneberg Allan, Ross-Hansen Katrine, Carlsen Berit C, Meldgaard Michael, Szecsi Pal B, Stender Steen, Menné Torkil, Johansen Jeanne D

Abstract excerpt

BACKGROUND: Although heterozygous filaggrin gene (FLG) mutation carriers seem to have an increased risk of atopic, irritant and allergic nickel dermatitis, it remains unclear whether the risk of contact sensitization to allergens other than nickel is also elevated in FLG mutation carriers. OBJECTIVES: We hypothesized that heterozygous FLG mutation carriers who suffer from dermatitis will have strongly reduced or...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23343419
DOI: 10.1111/cod.12021

Genes

FLG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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