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Article

Loss-of-function polymorphisms in the filaggrin gene are associated with an increased susceptibility to chronic irritant contact dermatitis: a case-control study.

The British journal of dermatology - 1 Sept 2008

de Jongh C M, Khrenova L, Verberk M M, Calkoen F, van Dijk F J H, Voss H, John S M, Kezic S

Abstract excerpt

BACKGROUND: Polymorphisms in the filaggrin (FLG) gene, which result in loss of filaggrin production, may alter the skin barrier and are a well-known predisposing factor for atopic dermatitis. OBJECTIVES: As a compromised skin barrier and atopic dermatitis are risk factors for chronic irritant contact dermatitis (CICD), our objective was to determine whether polymorphisms in the FLG gene contribute towards...

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Identifiers

PMID: 18637008
DOI: 10.1111/j.1365-2133.2008.08730.x

Genes

FLG

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Loss-of-function polymorphisms in the filaggrin gene are associated with an increased susceptibility to chronic irritant contact dermatitis: a case-control study.PMID 18637008Read ↗

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